Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117181 | 1.00 | TMPRSS2 (0.42) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL12243239 | 1.00 | TMPRSS2 (0.42) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL16730747 | 1.00 | TMPRSS2 (0.42) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL17109563 | 1.00 | TMPRSS2 (0.42) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL10120471 | 1.00 | TMPRSS2 (0.42) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL15682912 | 0.91 | TMPRSS2 (0.41) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL881677 | 0.90 | TMPRSS2 (0.40) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL15888889 | 0.90 | TMPRSS2 (0.40) | TMPRSS2ADORA2APIK3CDPOLRMTPI4KA | |
| SCHEMBL12393232 | 0.90 | TMPRSS2 (0.37) | TMPRSS2ADORA2APOLRMTPI4KAPI4K2B | |
| SCHEMBL12393404 | 0.89 | TMPRSS2 (0.41) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828409-B2 | Bridged-cyclo-ProTides as prodrugs of therapeutic nucleosides and nucleotides | ZHONG MINGHONG (US) | 2017-11-28 | — | — | US | disclosed |