Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.45 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Marein SCHEMBL620953 | 0.91 | GAA (1.00) | GAATDP1AKR1B1DPP4SNCA | |
| Marein SCHEMBL13255955 | 0.91 | GAA (1.00) | GAATDP1AKR1B1DPP4SNCA | |
| Marein SCHEMBL13227297 | 0.91 | GAA (1.00) | GAATDP1AKR1B1DPP4SNCA | |
| Marein SCHEMBL620954 | 0.91 | GAA (1.00) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL29456135 | 0.83 | GAA (0.81) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL25195145 | 0.78 | AKR1B1 (0.75) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL25209777 | 0.77 | AKR1B1 (0.71) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL30092342 | 0.77 | AKR1B1 (0.80) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL25195568 | 0.77 | AKR1B1 (0.71) | GAATDP1AKR1B1DPP4SNCA | |
| SCHEMBL30674920 | 0.77 | GAA (0.67) | GAATDP1AKR1B1DPP4SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | disclosed |