Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 4/20 | 0.32 |
| ▸ | CHUK | O15111 | 3/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375333 | 0.84 | CA12 (0.40) | CA12CA1CA9IKBKBCHUK | |
| SCHEMBL12422248 | 0.76 | MEN1 (0.46) | AHRCSNK2A1IKBKBCHUK | |
| SCHEMBL30310568 | 0.76 | MEN1 (0.46) | AHRCSNK2A1IKBKBCHUK | |
| SCHEMBL20535821 | 0.76 | CA12 (0.39) | CA12CA1CA9PREP | |
| SCHEMBL20355056 | 0.75 | AHR (0.39) | CA12CA1CA9AHR | |
| SCHEMBL29561134 | 0.75 | AHR (0.39) | CA12CA1CA9AHR | |
| SCHEMBL1274214 | 0.74 | CA12 (0.49) | CA12CA1CA9AHR | |
| SCHEMBL19782489 | 0.72 | CA12 (0.40) | CA12CA1CA9PREP | |
| SCHEMBL1751255 | 0.71 | MEN1 (0.57) | CA12CA1CA9AHRPREP | |
| SCHEMBL19782494 | 0.71 | CA12 (0.40) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009436-B1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC (US) | 2019-06-05 | — | — | EP | disclosed |
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |