SCHEMBL19645283

SCHEMBL19645283

O=C(OCc1ccccc1)c1ccc2ccc3ccccc3c2n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
EGLN1 Q9GZT9 1/20 0.52
KMT2A Q03164 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
MEN1 O00255 1/20 0.48
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 2/20 0.45
MAPK1 P28482 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2117639 0.88 MAPT (0.49) MAPTEGLN1KMT2ATDP1SLC6A2
SCHEMBL2118828 0.84 KMT2A (0.59) MAPTEGLN1KMT2ATDP1SLC6A2
SCHEMBL19645284 0.83 EGLN1 (0.67) MAPTEGLN1KMT2ATDP1SLC6A2
SCHEMBL6080222 0.82 HDAC3 (0.59) MAPTEGLN1KMT2AMEN1KDM4E
SCHEMBL8403275 0.81 MAPT (0.79) MAPTKMT2ATDP1SLC6A2SLC6A3
SCHEMBL22946291 0.78 TDP1 (0.61) MAPTKMT2ATDP1SLC6A2SLC6A3
SCHEMBL6081009 0.78 EGLN1 (0.47) MAPTEGLN1KMT2ATDP1SLC6A2
SCHEMBL28337295 0.77 KMT2A (0.47) MAPTKMT2AL3MBTL1MEN1KDM4E
SCHEMBL7036195 0.76 KDM4E (0.62) MAPTKMT2ATDP1MEN1KDM4E
SCHEMBL28486793 0.76 KMT2A (0.59) MAPTEGLN1KMT2ATDP1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2752907-B1 ORGANIC LIGHT EMITTING DIODE LG DISPLAY CO LTD (KR) 2019-07-17 EP disclosed
US-9831457-B2 Organic light emitting diode LG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-9831457-B2 Organic light emitting diode LG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed