Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNJ4 | P48050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496166 | 0.88 | GAA (0.49) | GAAKMT2AHSD17B10KCNJ4POLB | |
| Hydrochloric Acid SCHEMBL496077 | 0.87 | HSD17B10 (0.50) | GAAKMT2AHSD17B10KCNJ4POLB | |
| SCHEMBL19257998 | 0.81 | EPHX1 (0.52) | GAAKMT2AHSD17B10KCNJ4POLB | |
| SCHEMBL367115 | 0.81 | EPHX1 (0.52) | GAAKMT2AHSD17B10KCNJ4POLB | |
| SCHEMBL5913859 | 0.81 | EPHX1 (0.52) | GAAKMT2AHSD17B10KCNJ4POLB | |
| Hydrochloric Acid SCHEMBL6007905 | 0.80 | EPHX1 (0.50) | GAAKMT2AHSD17B10KCNJ4POLB | |
| SCHEMBL12087995 | 0.79 | POLB (0.56) | KMT2AHSD17B10POLBCYP2D6ATM | |
| SCHEMBL1085018 | 0.79 | POLB (0.56) | KMT2AHSD17B10POLBCYP2D6ATM | |
| SCHEMBL6549264 | 0.79 | POLB (0.56) | KMT2AHSD17B10POLBCYP2D6ATM | |
| SCHEMBL296051 | 0.79 | POLB (0.56) | KMT2AHSD17B10POLBCYP2D6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828349-B2 | 1-aryl-1-hydroxy-2,3-diamino-propyl amines, 1-heteroaryl-1-hydroxy-2,3-diamino-propyl amines and related compounds having analgesic and/or immuno stimulant activity | EXONHIT THERAPEUTICS SA (FR) | 2017-11-28 | — | — | US | disclosed |