Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 10/20 | 0.61 |
| ▸ | CLK3 | P49761 | 10/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.61 |
| ▸ | WNT1 | P04628 | 10/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20747711 | 0.93 | CLK2 (0.53) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19645506 | 0.92 | DYRK1A (0.59) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19645531 | 0.91 | CLK2 (0.51) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19645518 | 0.90 | CLK2 (0.77) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19645631 | 0.89 | CLK2 (0.66) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19645613 | 0.89 | DYRK1A (0.59) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19356556 | 0.89 | CLK2 (0.61) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL19363508 | 0.88 | CLK2 (0.48) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17583433 | 0.87 | CLK2 (0.79) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL17586916 | 0.86 | CLK2 (0.76) | CLK2CLK3DYRK1AWNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828372-B2 | 2-(1H-indazol-3-yl)-1H-imidazo[4,5-C]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-11-28 | — | — | US | disclosed |