Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 16/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966770 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1964208 | 0.85 | S1PR1 (0.56) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1964560 | 0.83 | S1PR1 (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1964962 | 0.82 | S1PR1 (0.64) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL2297403 | 0.77 | S1PR1 (0.61) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1966747 | 0.77 | S1PR1 (0.69) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1966161 | 0.76 | S1PR1 (0.68) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1966270 | 0.76 | S1PR1 (0.76) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1967851 | 0.76 | S1PR1 (0.77) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1970812 | 0.75 | S1PR1 (0.60) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |