Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719318 | 0.95 | MAPT (0.30) | MAPT | |
| SCHEMBL19309246 | 0.94 | — | — | |
| SCHEMBL25825965 | 0.81 | KDM4E (0.31) | MAPT | |
| SCHEMBL19646073 | 0.78 | KDM4E (0.38) | MAPTALDH1A1CYP2D6 | |
| SCHEMBL21719130 | 0.77 | KDM4E (0.31) | MAPT | |
| SCHEMBL21719396 | 0.75 | — | — | |
| SCHEMBL22066258 | 0.75 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL25101245 | 0.75 | — | — | |
| SCHEMBL23502540 | 0.74 | CNR2 (0.34) | ALDH1A1 | |
| SCHEMBL23502537 | 0.74 | CNR2 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828377-B2 | Heterocyclic compounds and uses thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2017-11-28 | — | — | US | disclosed |