Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | P2RY10 | O00398 | 6/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964153 | 1.00 | PLA2G2C (0.43) | PLA2G2CPLA2G2AP2RY10GPR34PPARG | |
| SCHEMBL1962712 | 1.00 | PLA2G2C (0.43) | PLA2G2CPLA2G2AP2RY10GPR34PPARG | |
| SCHEMBL1965023 | 0.97 | PLA2G2C (0.41) | PLA2G2CPLA2G2AP2RY10GPR34PPARG | |
| SCHEMBL1962218 | 0.96 | PLA2G2C (0.36) | PLA2G2CPLA2G2AP2RY10GPR34PPARG | |
| SCHEMBL1962701 | 0.91 | P2RY10 (0.42) | PLA2G2CPLA2G2AP2RY10GPR34GPR174 | |
| SCHEMBL1965773 | 0.90 | PLA2G2C (0.44) | PLA2G2CP2RY10GPR34PPARGPPARA | |
| SCHEMBL4435691 | 0.90 | PLA2G2C (0.44) | PLA2G2CP2RY10GPR34PPARGPPARA | |
| SCHEMBL1963907 | 0.90 | PLA2G2C (0.44) | PLA2G2CP2RY10GPR34PPARGPPARA | |
| SCHEMBL2311014 | 0.90 | PLA2G2C (0.44) | PLA2G2CP2RY10GPR34PPARGPPARA | |
| SCHEMBL4444982 | 0.90 | PLA2G2C (0.44) | PLA2G2CP2RY10GPR34PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |