⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443320 | 1.00 | — | — | |
| SCHEMBL20076214 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7343959 | 0.96 | — | — | |
| SCHEMBL3374972 | 0.82 | — | — | |
| SCHEMBL13970207 | 0.77 | — | — | |
| SCHEMBL20620900 | 0.72 | — | — | |
| SCHEMBL23395275 | 0.69 | — | — | |
| SCHEMBL25255160 | 0.69 | — | — | |
| SCHEMBL23132623 | 0.69 | — | — | |
| SCHEMBL20033517 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421465-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AS WELL AS PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2022-10-26 | — | — | EP | disclosed |
| US-20210171470-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS, INC. | 2021-06-10 | — | — | US | disclosed |
| US-20210040044-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. | 2021-02-11 | — | — | US | disclosed |
| WO-2020263848-A1 | PROCESSES AND INTERMEDIATES FOR PRODUCING DIAZASPIRO LACTAM COMPOUNDS | NAUREX INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-2875014-B1 | ANTI-MUCUS DRUGS AND USES THEREFOR | UNIV WASHINGTON (US) | 2017-11-29 | — | — | EP | disclosed |