Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412551 | 0.97 | CYP2C9 (0.50) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL8771591 | 0.97 | CYP2C9 (0.50) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11405579 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11418435 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11407420 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11405181 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11406106 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL11416560 | 0.96 | CYP2C9 (0.49) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL10967806 | 0.94 | CYP2C9 (0.50) | CYP2C9MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL10967804 | 0.94 | CYP2C9 (0.50) | CYP2C9MAPTLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970326-B1 | SUBSTITUTED 5,6-RING-FUSED NAPHTHOPYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-11-29 | — | — | EP | disclosed |