Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.76 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.76 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 3/20 | 0.72 |
| ▸ | LYN | P07948 | 1/20 | 0.72 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | TEK | Q02763 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 3/20 | 0.64 |
| ▸ | ITK | Q08881 | 1/20 | 0.63 |
| ▸ | TEC | P42680 | 1/20 | 0.63 |
| ▸ | TXK | P42681 | 1/20 | 0.63 |
| ▸ | BMX | P51813 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25068900 | 0.89 | BTK (0.89) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL19649129 | 0.89 | BTK (0.89) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL24196790 | 0.87 | BTK (0.75) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL21341768 | 0.86 | BTK (1.00) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25069063 | 0.86 | BTK (0.75) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25933030 | 0.86 | BTK (0.75) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL19209534 | 0.85 | BTK (0.83) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL5803823 | 0.85 | BTK (0.86) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25068925 | 0.85 | BTK (0.80) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL22737178 | 0.85 | BTK (0.80) | BTKNUDT14NUDT5LCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248979-B1 | NOVEL INHIBITOR OF FLT3 KINASE AND USE THEREOF | HEFEI INST PHYSICAL SCI CAS (CN) | 2021-04-14 | — | — | EP | disclosed |
| EP-3248979-A1 | NOVEL INHIBITOR OF FLT3 KINASE AND USE THEREOF | Hefei Institutes of Physical Sicence, Chinese Academy of Sciences (CN) | 2017-11-29 | — | — | EP | disclosed |