SCHEMBL1965074

SCHEMBL1965074

O[SiH2]CCCOCC1CO1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.57
ALDH1A1 P00352 5/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPK1 P28482 1/20 0.39
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30660764 0.83 TSHR (0.71) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17549552 0.80 TSHR (1.00) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13974192 0.80 TSHR (1.00) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17549553 0.80 TSHR (1.00) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17549551 0.80 TSHR (1.00) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24547426 0.80 TSHR (0.90) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL100304 0.80 TSHR (0.90) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL21272 0.80 TSHR (1.00) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4321971 0.80 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL31312729 0.80 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4656685-A1 CONDUCTIVE SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-03 EP claimed
WO-2025033098-A1 LIQUID SILICONE RUBBER COMPOSITION 信越化学工業株式会社 2025-02-13 WO claimed
WO-2024157680-A1 CONDUCTIVE SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF 信越化学工業株式会社 2024-08-02 WO claimed
EP-1405852-B9 DIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2013-03-27 EP claimed
EP-1577301-B1 Antithrombotic diaminocyclohexane derivatives DAIICHI SANKYO CO LTD (JP) 2012-09-12 EP claimed
EP-1405852-B1 DIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2012-08-01 EP claimed
EP-0486196-B1 Highly tintable abrasion resistant coatings SDC COATINGS INC (US) 2000-02-02 EP claimed
EP-0594047-B1 Arylazo chromoionophores BAYER AG (US) 2000-01-05 EP claimed
EP-0917550-A4 SILICON COATING COMPOSITIONS AND USES THEREOF BLUE RIVER INTERNATIONAL L L C (US) 1999-12-29 EP claimed
US-5929159-A Oligomeric silicon coating compositions, articles coated therewith and method for forming coating composition and coated articles based thereon ADSIL LC (US) 1999-07-27 US claimed
CN-1039343-C Highly tintable abrasion resistant coatings SWEDLOW INC (US) 1998-07-29 CN claimed
WO-1998018855-A1 SILICON COATING COMPOSITIONS AND USES THEREOF BLUE RIVER INTERNATIONAL, L.L.C. (US) 1998-05-07 WO claimed
WO-1997045498-A1 HIGHLY TINTABLE, ABRASION-RESISTANT COATING COMPOSITIONS SDC COATINGS, INC. (US) 1997-12-04 WO claimed
EP-0407174-B1 Highly tintable abrasion resistant coatings PILKINGTON AEROSPACE INC (US) 1994-10-12 EP claimed
EP-0486196-A2 Highly tintable abrasion resistant coatings SWEDLOW, INC. (US) 1992-05-20 EP claimed
US-5102695-A Blend of colloidal silica, polysiloxane and alkylated amine formaldehyde compound SWEDLOW, INC. (US) 1992-04-07 US claimed
US-5073588-A Solvent free HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-12-17 US claimed
US-5013608-A Polysilsesquioxanes, coatings for eyeglasses, windows, ultraviolet radiation protection SWEDLOW, INC. (US) 1991-05-07 US claimed
CN-1049171-A The dyeed coating of highly abrasion-resistant SWEDLOW INC (US) 1991-02-13 CN claimed
EP-0407174-A2 Highly tintable abrasion resistant coatings Pilkington Aerospace Inc. (US) 1991-01-09 EP claimed