Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.66 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.66 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 17/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734653 | 0.87 | MAP4K4 (0.87) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1965060 | 0.81 | MAP4K4 (0.67) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL13045475 | 0.80 | MAP4K4 (0.87) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL3734659 | 0.80 | MAP4K4 (0.77) | MAP4K4MINK1S1PR1S1PR3S1PR5 | |
| SCHEMBL3739728 | 0.80 | MAP4K4 (0.83) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1966060 | 0.80 | MAP4K4 (1.00) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| Acetic Acid SCHEMBL3745831 | 0.79 | MAP4K4 (0.84) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2339549 | 0.78 | MAP4K4 (0.72) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL2339534 | 0.78 | MAP4K4 (0.72) | MAP4K4MINK1DYRK3MARK3PLK1 | |
| SCHEMBL1969164 | 0.77 | MAP4K4 (0.78) | MAP4K4MINK1DYRK3MARK3PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509424-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |