⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801461 | 0.82 | — | — | |
| SCHEMBL687303 | 0.70 | — | — | |
| SCHEMBL7746277 | 0.70 | — | — | |
| SCHEMBL28286557 | 0.67 | — | — | |
| SCHEMBL7080726 | 0.64 | — | — | |
| SCHEMBL148410 | 0.64 | — | — | |
| SCHEMBL24744 | 0.64 | — | — | |
| SCHEMBL13449403 | 0.64 | — | — | |
| SCHEMBL11225334 | 0.64 | — | — | |
| SCHEMBL1885284 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132135-B2 | Method of treating organophosphorous poisoning | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2334182-A1 | METHOD OF TREATING ORGANOPHOSPHOROUS POISONING | University of Maryland, Baltimore (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010025259-A1 | METHOD OF TREATING ORGANOPHOSPHOROUS POISONING | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20090023706-A1 | Method of Treating Organophosphorous Poisoning | UNIVERSITY OF MARYLAND BALTIMORE (US) | 2009-01-22 | — | — | US | disclosed |