Ether

Ether

SCHEMBL1965333

CCOCC.O=C(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
ALDH1A1 P00352 2/20 0.44
ELANE P08246 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
USP2 O75604 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALOX15 P16050 2/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
HPGD P15428 2/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL3801023 0.89 MAPT (0.48) MAPTALDH1A1ELANEUSP2TDP1
Ether SCHEMBL2396247 0.88 ELANE (0.49) MAPTALDH1A1ELANESMN1; SMN2TDP1
SCHEMBL27861489 0.86 MAPT (0.54) MAPTALDH1A1USP2TDP1ATM
Acetic Acid Phenyl Ester SCHEMBL1830444 0.86 ELANE (0.58) MAPTALDH1A1ELANESMN1; SMN2TDP1
SCHEMBL9353455 0.84 TDP1 (0.54) MAPTALDH1A1ELANESMN1; SMN2USP2
SCHEMBL27352197 0.84 TDP1 (0.54) MAPTALDH1A1ELANESMN1; SMN2USP2
SCHEMBL9241160 0.84 TDP1 (0.54) MAPTALDH1A1ELANESMN1; SMN2USP2
SCHEMBL18073 0.84 TDP1 (0.54) MAPTALDH1A1ELANESMN1; SMN2USP2
SCHEMBL9353461 0.84 TDP1 (0.54) MAPTALDH1A1ELANESMN1; SMN2USP2
Ether SCHEMBL10778923 0.84 ZDHHC2 (0.55) MAPTALDH1A1ELANESMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2510401-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2015-02-25 EP disclosed
US-8785089-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-07-22 US disclosed
EP-2510401-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2012-10-17 EP disclosed
US-20120243904-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-09-27 US disclosed
WO-2011071093-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-16 WO disclosed