Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280349 | 0.99 | CCNE1 (0.41) | CCNE1CDK2CCNE2CNR1CNR2 | |
| SCHEMBL14280342 | 0.96 | CCNE1 (0.42) | CCNE1CDK2CCNE2CNR1CNR2 | |
| SCHEMBL14280341 | 0.92 | CCNE1 (0.44) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL14280348 | 0.87 | CCNE1 (0.45) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL14280343 | 0.85 | CCNE1 (0.42) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL14280344 | 0.82 | CCNE1 (0.43) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL92445 | 0.81 | CCNE1 (0.48) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL14280346 | 0.77 | CCNE1 (0.42) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL91890 | 0.74 | SMN1; SMN2 (0.51) | CCNE1CDK2CCNE2MEN1KMT2A | |
| SCHEMBL2623686 | 0.74 | SMN1; SMN2 (0.51) | CCNE1CDK2CCNE2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | disclosed |