Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19655854 | 0.89 | MAPK8 (0.38) | MAPK8L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL19641826 | 0.87 | MAPT (0.39) | MAPK8L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL21038249 | 0.86 | MAPK8 (0.40) | MAPK8L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL23616611 | 0.77 | DHODH (0.32) | MAPK8KMT2ASCN9A | |
| SCHEMBL21039333 | 0.76 | MAPT (0.40) | MAPK8L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL14639521 | 0.76 | MAPK8 (0.41) | MAPK8L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL21038259 | 0.76 | MEN1 (0.33) | MAPK8KMT2AP2RY1HTR1APDE10A | |
| SCHEMBL21032979 | 0.75 | TSHR (0.44) | ALDH1A1KMT2ALMNANPC1MAPT | |
| SCHEMBL19655801 | 0.75 | MEN1 (0.32) | MAPK8KMT2AP2RY1HTR1ADRD2 | |
| SCHEMBL21038603 | 0.75 | MAPK8 (0.41) | MAPK8L3MBTL1ALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101533-A1 | CRYSTALLINE FORMS OF ETHYL 2-[[3-[[3-CHLORO-5-FLUORO-6-[3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)PYRIMIDIN-1-YL]-2-PYRIDYL]OXY]-2-PYRIDYL]OXY]ACETATE | BASF SE (DE) | 2019-05-31 | — | — | WO | disclosed |
| WO-2017202768-A1 | HERBICIDAL URACILPYRID | BASF SE (DE) | 2017-11-30 | — | — | WO | disclosed |