SCHEMBL19656148

SCHEMBL19656148

O=C(Oc1cccc2cccc(OC(=O)C3CCCC3)c12)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.54
MEN1 O00255 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
RAB9A P51151 1/20 0.54
ELANE P08246 2/20 0.50
POLB P06746 2/20 0.50
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
STAT3 P40763 1/20 0.48
LMNA P02545 1/20 0.47
METAP2 P50579 1/20 0.47
METAP1 P53582 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 3/20 0.45
JAK2 O60674 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2405154 0.99 KMT2A (0.52) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL19642799 0.94 KMT2A (0.60) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL19642932 0.91 POLB (0.48) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL29563656 0.91 POLB (0.48) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL2403812 0.88 KMT2A (0.53) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL17502630 0.88 KMT2A (0.50) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL17502681 0.88 KMT2A (0.50) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL17502753 0.88 KMT2A (0.50) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL2406824 0.87 ESR1 (0.61) KMT2AMEN1L3MBTL1RAB9AELANE
SCHEMBL2402495 0.87 STAT3 (0.45) KMT2AMEN1L3MBTL1RAB9AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
CN-109790238-B Non-phthalate donors for polyolefin catalysts 布拉斯科美国公司 2021-12-31 CN disclosed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US disclosed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US disclosed
EP-3668643-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS Braskem America, Inc. (US) 2020-06-24 EP disclosed
US-10662267-B2 Non-phthalate donor for polyolefin catalysts W.R. GRACE & CO. -CONN. (US) 2020-05-26 US disclosed
US-20190270831-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W. R. GRACE & CO. - CONN. 2019-09-05 US disclosed
WO-2019036376-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS BRASKEM AMERICA, INC. (US) 2019-02-21 WO disclosed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO disclosed