SCHEMBL19656160

SCHEMBL19656160

O=C(/C=C/c1ccccc1)Oc1cccc2cccc(OC(=O)c3ccccc3-c3ccccc3)c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.51
LMNA P02545 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MEN1 O00255 1/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
ALDH1A1 P00352 2/20 0.45
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TUBB4A P04350 3/20 0.41
TUBB P07437 3/20 0.41
TUBA3C P0DPH7 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19642789 1.00 KMT2A (0.51) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL29563698 1.00 KMT2A (0.51) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19656163 0.85 KMT2A (0.66) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL29563665 0.83 KMT2A (0.53) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19656082 0.83 KMT2A (0.53) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642963 0.83 KMT2A (0.53) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642861 0.83 KMT2A (0.57) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642860 0.83 KMT2A (0.57) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642788 0.82 KMT2A (0.52) KMT2ALMNAL3MBTL1MEN1HTT
SCHEMBL19642786 0.81 KMT2A (0.53) KMT2ALMNAL3MBTL1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370854-B2 Non-phthalate donor for polyolefin catalysts BRASKEM AMERICA, INC. (US) 2022-06-28 US disclosed
US-20200223958-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 2020-07-16 US disclosed
EP-3668643-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS Braskem America, Inc. (US) 2020-06-24 EP disclosed
US-10662267-B2 Non-phthalate donor for polyolefin catalysts W.R. GRACE & CO. -CONN. (US) 2020-05-26 US disclosed
US-20190270831-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W. R. GRACE & CO. - CONN. 2019-09-05 US disclosed
WO-2019036376-A1 BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS BRASKEM AMERICA, INC. (US) 2019-02-21 WO disclosed
WO-2017204811-A1 NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS W.R. GRACE & CO. -CONN. (US) 2017-11-30 WO disclosed