Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 8/20 | 0.50 |
| ▸ | MMP3 | P08254 | 4/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478303 | 0.91 | HDAC2 (0.53) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL19640509 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL19640510 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL31685984 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL16114842 | 0.81 | MEN1 (0.56) | HDAC8HDAC6HPGDALDH1A1KMT2A | |
| SCHEMBL7894643 | 0.81 | MEN1 (0.56) | HDAC8HDAC6HPGDALDH1A1KMT2A | |
| SCHEMBL9503736 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL26616556 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL6136527 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL14997395 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250288559-A1 | PREP BINDING LIGANDS | POLKU THERAPEUTICS OY (FI) | 2025-09-18 | — | — | US | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |
| US-20170342046-A1 | Fatty Acid Cysteine-Based Conjugates and Their Use in Treating Medical Disorders | CATABASIS PHARMACEUTICALS, INC. | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342046-A1 | Fatty Acid Cysteine-Based Conjugates and Their Use in Treating Medical Disorders | CPT2, FABP1, ACAA2 | SMN1; SMN2 2317/4885HDAC1 1243/4885HDAC3 437/4885 |
| US-20250288559-A1 | PREP BINDING LIGANDS | PREP, ERAP2, CTSA | SMN1; SMN2 3319/4885HDAC1 287/4885HDAC3 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.