Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 13/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258698 | 0.81 | HTR2C (0.53) | HTR2CHTR2AARCA1CA2 | |
| SCHEMBL5537547 | 0.80 | AR (0.40) | HTR2CARPGRCA1CA2 | |
| SCHEMBL31511252 | 0.79 | HTR2B (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL20571939 | 0.79 | HTR2B (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL5537541 | 0.79 | AR (0.39) | ARPGR | |
| SCHEMBL31000351 | 0.79 | HTR2B (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL17785801 | 0.79 | HTR2B (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL22050032 | 0.79 | HTR2B (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL19656942 | 0.79 | HTR2C (0.46) | HTR2CHTR2AARPGRCA1 | |
| SCHEMBL16359911 | 0.79 | F12 (0.40) | F12F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205296-A1 | AMINOACYLINDAZOLE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES | THE ROCKEFELLER UNIVERSITY (US) | 2017-11-30 | — | — | WO | disclosed |