Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | DCK | P27707 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580898 | 1.00 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL5717526 | 1.00 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL2580896 | 1.00 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL8621829 | 0.88 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL13871553 | 0.88 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL14577836 | 0.88 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL4129272 | 0.88 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL3195379 | 0.88 | ALB (0.55) | ALBDNMT1ADRB1POLGDCK | |
| SCHEMBL2583043 | 0.88 | DNMT1 (0.42) | ALBDNMT1ADRB1LMNASMN1; SMN2 | |
| SCHEMBL2583037 | 0.88 | DNMT1 (0.42) | ALBDNMT1ADRB1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201585-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | GENEA IP HOLDINGS PTY LTD (AU) | 2017-11-30 | — | — | WO | disclosed |