Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 20/20 | 0.73 |
| ▸ | CECR2 | Q9BXF3 | 7/20 | 0.58 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 6/20 | 0.57 |
| ▸ | TAF1 | P21675 | 5/20 | 0.57 |
| ▸ | BRD2 | P25440 | 1/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.50 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657243 | 0.87 | BRD9 (0.73) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL17749801 | 0.84 | BRD9 (1.00) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL17749800 | 0.84 | BRD9 (1.00) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL19657253 | 0.81 | BRD9 (0.73) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL19657355 | 0.77 | BRD9 (0.72) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL19657240 | 0.77 | BRD9 (0.72) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL17749877 | 0.77 | BRD9 (1.00) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL17749878 | 0.77 | BRD9 (1.00) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL19657246 | 0.75 | BRD9 (0.74) | BRD9CECR2BRD7BRD4TAF1 | |
| SCHEMBL19657250 | 0.75 | BRD9 (0.70) | BRD9CECR2BRD7BRD4TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183009-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183009-B2 | Therapeutic compounds and uses thereof | BRD4, BRDT, BRPF3 | BRD9 12/4885CECR2 246/4885BRD7 8/4885 |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRPF3 | BRD9 12/4885CECR2 246/4885BRD7 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.