Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966786 | 1.00 | PIM1 (0.78) | PIM1PIM2 | |
| SCHEMBL1970695 | 0.92 | PIM1 (0.76) | PIM1PIM2 | |
| SCHEMBL1968345 | 0.92 | PIM1 (0.76) | PIM1PIM2 | |
| SCHEMBL1966512 | 0.89 | PIM1 (0.78) | PIM1PIM2 | |
| SCHEMBL1970639 | 0.89 | PIM1 (0.78) | PIM1PIM2 | |
| SCHEMBL1976976 | 0.88 | PIM1 (1.00) | PIM1PIM2 | |
| SCHEMBL1978264 | 0.88 | PIM1 (1.00) | PIM1PIM2 | |
| SCHEMBL12589290 | 0.85 | PIM1 (0.77) | PIM1PIM2 | |
| SCHEMBL1973634 | 0.82 | PIM1 (1.00) | PIM1PIM2 | |
| SCHEMBL1977155 | 0.82 | PIM1 (1.00) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334677-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010022076-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-02-25 | — | — | WO | disclosed |