Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 6/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986201 | 0.85 | CA1 (0.50) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL26995925 | 0.84 | CA1 (0.56) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL8187865 | 0.84 | CA1 (0.56) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL3423227 | 0.84 | CA1 (0.56) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL3553296 | 0.83 | CA1 (0.59) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL18843235 | 0.83 | CA1 (0.59) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL13764949 | 0.83 | CA1 (0.59) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL28425565 | 0.81 | TSHR (0.48) | CA1CA2TDP1L3MBTL1HTT | |
| SCHEMBL11121387 | 0.81 | TSHR (0.48) | CA1CA2TDP1L3MBTL1HTT | |
| SCHEMBL27894678 | 0.81 | TSHR (0.48) | CA1CA2TDP1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205791-A1 | CALLYSPONGIOLIDE, ANALOGS THEREOF AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2017-11-30 | — | — | WO | disclosed |