Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.63 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722594 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19448474 | 0.78 | BRD4 (0.74) | BRD4MALT1 | |
| SCHEMBL22593052 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19661830 | 0.78 | BRD4 (0.66) | BRD4MALT1 | |
| SCHEMBL19448475 | 0.77 | BRD4 (0.72) | BRD4MALT1 | |
| SCHEMBL19439125 | 0.77 | BRD4 (0.86) | BRD4MALT1 | |
| SCHEMBL19448188 | 0.76 | BRD4 (0.71) | BRD4MALT1 | |
| SCHEMBL22694648 | 0.75 | BRD4 (1.00) | BRD4 | |
| SCHEMBL22694655 | 0.74 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19457553 | 0.73 | BRD4 (0.67) | BRD4MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017202742-A1 | PYRIDINE DICARBOXAMIDE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-11-30 | — | — | WO | disclosed |