Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.49 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26156344 | 0.95 | KMT2A (0.62) | KMT2AMDM2TLR2CPB1CPB2 | |
| SCHEMBL26156345 | 0.93 | KMT2A (0.64) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL16925664 | 0.93 | KMT2A (0.64) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL16592017 | 0.91 | KMT2A (0.58) | KMT2AMDM2TLR2 | |
| SCHEMBL14147622 | 0.91 | MDM2 (0.57) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL14770861 | 0.91 | MDM2 (0.57) | KMT2AMDM2TLR2MDM4TP53 | |
| Hydrochloric Acid SCHEMBL30744256 | 0.90 | MDM2 (0.56) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL260631 | 0.89 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL178698 | 0.89 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 | |
| SCHEMBL29528567 | 0.89 | KMT2A (0.66) | KMT2AMDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |