Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.54 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 2/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913409 | 1.00 | POLB (0.57) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL21787190 | 0.96 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL23734250 | 0.96 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL23734156 | 0.96 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL24913408 | 0.95 | POLB (0.56) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL19662616 | 0.93 | POLB (0.55) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL18844553 | 0.91 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL24895768 | 0.91 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL19175178 | 0.91 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL18844550 | 0.91 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |