Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 11/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914049 | 0.82 | SCN4A (0.39) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL17159714 | 0.81 | SCN4A (0.36) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL2715708 | 0.80 | SCN4A (0.41) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL4550829 | 0.80 | SCN4A (0.45) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL2714554 | 0.80 | SCN4A (0.38) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL27931943 | 0.80 | SCN4A (0.38) | GLAMAPTSCN4ANR3C1LMNA | |
| Hydrochloric Acid SCHEMBL28093621 | 0.79 | GLA (0.39) | GLAMAPTSCN4ALMNASCN1A | |
| SCHEMBL4550431 | 0.79 | SCN4A (0.46) | SCN4ALMNASCN1ASCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL2717073 | 0.79 | SCN4A (0.44) | GLAMAPTSCN4ALMNASCN1A | |
| Hydrochloric Acid SCHEMBL2716056 | 0.77 | SCN5A (0.46) | GLAMAPTSCN4ALMNASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914597-B1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2017-12-06 | — | — | EP | disclosed |