Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005363 | 0.87 | CA12 (0.35) | CA12CA1CA2CA9ALB | |
| SCHEMBL19664942 | 0.84 | SCN9A (0.32) | SCN9A | |
| SCHEMBL16005351 | 0.84 | MAPT (0.39) | CA12CA1CA2CA9ALB | |
| SCHEMBL16005362 | 0.81 | CA12 (0.33) | CA12CA1CA2CA9ALB | |
| SCHEMBL16005162 | 0.80 | MAPT (0.45) | CA12CA1CA2CA9ALB | |
| SCHEMBL16005285 | 0.79 | MAPT (0.41) | CA12CA1CA2CA9ALB | |
| SCHEMBL19664963 | 0.77 | MAPT (0.36) | KMT2AMEN1MAPTSCN9ANPSR1 | |
| SCHEMBL16005753 | 0.77 | MAPT (0.40) | CA12CA1CA2CA9ALB | |
| SCHEMBL16005092 | 0.77 | MAPT (0.49) | CA12CA1CA2CA9ALB | |
| SCHEMBL16005098 | 0.75 | MAPT (0.46) | CA12CA1CA2CA9ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774914-B1 | N-BENZYLANILINE DERIVATIVE AND USES THEREOF | UNIV NANJING MEDICAL (CN) | 2017-12-06 | — | — | EP | claimed |