Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.74 |
| ▸ | HTR3A | P46098 | 2/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.54 |
| ▸ | WNT1 | P04628 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963578 | 1.00 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1NTRK1 | |
| SCHEMBL1964670 | 1.00 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1NTRK1 | |
| SCHEMBL1966241 | 0.91 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1A | |
| SCHEMBL1966557 | 0.91 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1A | |
| SCHEMBL1963740 | 0.88 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL5996566 | 0.88 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL1966879 | 0.88 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL1965460 | 0.88 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL1964878 | 0.88 | CHRNA7 (0.76) | CHRNA7HTR3ADYRK1AWNT1 | |
| SCHEMBL1965825 | 0.87 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530590-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | claimed |
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |