SCHEMBL19667498

SCHEMBL19667498

Br[Mg]Br.Fc1c[c]cc(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28112019 0.84
SCHEMBL27776989 0.84
SCHEMBL28112017 0.84
SCHEMBL27990959 0.82
Zinc Chloride SCHEMBL28227137 0.77
SCHEMBL2288994 0.74
SCHEMBL27833422 0.72
SCHEMBL27811632 0.71 CA12 (0.36)
SCHEMBL19667324 0.70
SCHEMBL2284666 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307475-A Preparation method of stable isotope labeled fluxapyroxad internal standard reagent 谱同生物医药科技(常州)有限公司 2024-07-09 CN disclosed
US-10709709-B2 Substituted carbonucleoside derivatives useful as anticancer agents PFIZER INC. (US) 2020-07-14 US disclosed
US-20190111060-A1 SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER INC. (US) 2019-04-18 US disclosed
CN-108276294-A A kind of preparation method of fluorine-containing benzidine 上海康鹏科技有限公司 2018-07-13 CN disclosed
CN-107488113-A A kind of method for synthesizing o-aminobiphenyl class compound 上海泰禾国际贸易有限公司 2017-12-19 CN disclosed
US-20170348313-A1 SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER INC. (US) 2017-12-07 US disclosed
CN-106103404-B The preparation and application of biphenol compound 迈克斯(如东)化工有限公司 2017-11-24 CN disclosed
CN-106103404-A The preparation of biphenol compound and application 迈克斯(如东)化工有限公司 2016-11-09 CN disclosed