Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934924 | 0.98 | IGF1R (0.52) | RXFP1MAPTNPC1RAB9AIGF1R | |
| SCHEMBL196063 | 0.93 | RXFP1 (0.60) | RXFP1MAPTNPC1RAB9AHPGD | |
| SCHEMBL196744 | 0.92 | MAPT (0.58) | RXFP1MAPTNPC1RAB9AHPGD | |
| SCHEMBL196512 | 0.90 | MAPT (0.55) | RXFP1MAPTNPC1RAB9AHPGD | |
| SCHEMBL30637139 | 0.88 | GRM4 (0.51) | RXFP1MAPTNPC1RAB9AGRM4 | |
| SCHEMBL29501836 | 0.88 | GRM4 (0.51) | RXFP1MAPTNPC1RAB9AGRM4 | |
| SCHEMBL196780 | 0.88 | GRM4 (0.51) | RXFP1MAPTNPC1RAB9AGRM4 | |
| SCHEMBL1976142 | 0.88 | RXFP1 (0.53) | RXFP1MAPTNPC1RAB9AHPGD | |
| SCHEMBL196377 | 0.87 | GRM4 (0.49) | RXFP1MAPTNPC1RAB9AGRM4 | |
| SCHEMBL935627 | 0.87 | RXFP1 (0.51) | RXFP1MAPTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500255-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2323661-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | Universiteit Leiden (NL) | 2011-05-25 | — | — | EP | claimed |
| WO-2010020981-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | UNIVERSITEIT LEIDEN (NL) | 2010-02-25 | — | — | WO | claimed |