Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16968037 | 0.76 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL18986003 | 0.75 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL21054437 | 0.74 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL28956672 | 0.74 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19685238 | 0.72 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| Ammonia Solution, Strong SCHEMBL28956673 | 0.72 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL16968042 | 0.71 | TTK (0.51) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL15885489 | 0.71 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19668085 | 0.70 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL18985739 | 0.70 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207534-A1 | SUBSTITUTED HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-12-07 | — | — | WO | disclosed |