Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.46 |
| ▸ | PNP | P00491 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 6/20 | 0.42 |
| ▸ | AGL | P35573 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.41 |
| ▸ | GANC | Q8TET4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740184 | 1.00 | MGAM (0.46) | MGAMPNPGLAAGLGAA | |
| SCHEMBL505960 | 0.77 | PNP (0.54) | MGAMPNPGLAAGLGAA | |
| SCHEMBL505709 | 0.75 | PNP (0.64) | PNP | |
| SCHEMBL8246938 | 0.75 | PNP (0.64) | PNP | |
| SCHEMBL5606527 | 0.75 | PNP (0.64) | PNP | |
| Hydrochloric Acid SCHEMBL4830734 | 0.74 | PNP (0.63) | PNP | |
| SCHEMBL15740153 | 0.64 | PNP (0.59) | PNP | |
| SCHEMBL15740185 | 0.64 | MGAM (0.58) | MGAMPNPGLAAGLGAA | |
| SCHEMBL15593220 | 0.63 | GLA (1.00) | MGAMGLAAGLGAAGBA1 | |
| SCHEMBL2435520 | 0.63 | GLA (1.00) | MGAMGLAAGLGAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |