Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 19/20 | 0.80 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740317 | 1.00 | PNP (0.80) | PNPHPRT1 | |
| SCHEMBL15740319 | 1.00 | PNP (0.80) | PNPHPRT1 | |
| Forodesine SCHEMBL3896676 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL21386033 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15740194 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL2292668 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15318145 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15740309 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL15373311 | 0.89 | PNP (1.00) | PNPHPRT1 | |
| Forodesine SCHEMBL17161840 | 0.88 | PNP (1.00) | PNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |