SCHEMBL19671128

SCHEMBL19671128

Nc1ncnc2c(C3C[C@@H](O)C(CO)N3)c[nH]c12

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 4/20 0.64
MTAP Q13126 13/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15740137 1.00 PNP (0.64) PNPMTAP
SCHEMBL505570 0.86 PNP (0.65) PNPMTAP
Hydrochloric Acid SCHEMBL4841864 0.85 PNP (0.64) PNPMTAP
SCHEMBL13759695 0.78 PNP (0.64) PNPMTAP
SCHEMBL20850785 0.78 PNP (1.00) PNP
SCHEMBL3889067 0.78 PNP (0.64) PNPMTAP
SCHEMBL19671081 0.78 PNP (0.64) PNPMTAP
Galidesivir SCHEMBL25424734 0.78 PNP (1.00) PNPMTAP
SCHEMBL13765271 0.78 PNP (0.56) PNPMTAP
SCHEMBL19671054 0.78 PNP (0.56) PNPMTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3251674-A2 ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES BioCryst Pharmaceuticals, Inc. (US) 2017-12-06 EP disclosed