Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17430355 | 0.90 | LRRK2 (0.49) | LRRK2 | |
| SCHEMBL16025655 | 0.89 | LRRK2 (0.50) | LRRK2 | |
| SCHEMBL17430380 | 0.88 | LRRK2 (0.61) | LRRK2 | |
| SCHEMBL16025886 | 0.87 | LRRK2 (0.61) | LRRK2 | |
| SCHEMBL17430357 | 0.86 | CKS1B (0.42) | LRRK2 | |
| SCHEMBL17430370 | 0.85 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL16025701 | 0.85 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL16025959 | 0.84 | LRRK2 (0.63) | LRRK2 | |
| SCHEMBL16025582 | 0.84 | LRRK2 (0.49) | LRRK2 | |
| SCHEMBL16025597 | 0.83 | LRRK2 (0.47) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964221-B1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME (US) | 2017-12-06 | — | — | EP | disclosed |