⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967223 | 0.81 | — | — | |
| SCHEMBL1967230 | 0.72 | — | — | |
| SCHEMBL5148484 | 0.72 | — | — | |
| SCHEMBL6538046 | 0.70 | — | — | |
| SCHEMBL133406 | 0.67 | — | — | |
| SCHEMBL597791 | 0.66 | — | — | |
| SCHEMBL11126751 | 0.65 | — | — | |
| SCHEMBL552638 | 0.65 | — | — | |
| SCHEMBL4450140 | 0.65 | — | — | |
| SCHEMBL339491 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012956-B2 | Tropane compounds | EXELIXIS, INC. (US) | 2011-09-06 | — | — | US | claimed |
| EP-2074120-B1 | TROPANE COMPOUNDS | EXELIXIS INC (US) | 2010-03-03 | — | — | EP | claimed |
| US-20090318502-A1 | Pharmaceutical Compositions Comprising a Hypoglycemic Agent and Methods of Using Same | INTRANASAL THERAPEUTICS, INC. (US) | 2009-12-24 | — | — | US | claimed |
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | claimed |
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | claimed |
| WO-2007111933-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYPOGLYCEMIC AGENT AND METHODS OF USING SAME | INTRANASAL THERAPEUTICS , INC. (US) | 2007-10-04 | — | — | WO | claimed |
| US-8012956-B2 | Tropane compounds | EXELIXIS, INC. (US) | 2011-09-06 | — | — | US | disclosed |
| EP-2334659-A2 | PHENYL MALONIC ACID DERIVATIVES | STADA ARZNEIMITTEL AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010028842-A2 | PHENYL MALONIC ACID DERIVATIVES | STADA ARZNEIMITTEL AG (DE) | 2010-03-18 | — | — | WO | disclosed |
| EP-2074120-B1 | TROPANE COMPOUNDS | EXELIXIS INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-20090318502-A1 | Pharmaceutical Compositions Comprising a Hypoglycemic Agent and Methods of Using Same | INTRANASAL THERAPEUTICS, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-0099017-A2 | Phenyl-acetic-acid derivatives, their preparation and pharmaceutical compostions containing them | Dr. Karl Thomae GmbH (DE) | 1984-01-25 | — | — | EP | disclosed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0063826-A2 | 2-Amino-benzoic-acid derivatives, their preparation and their use as medicines or intermediates | Dr. Karl Thomae GmbH (DE) | 1982-11-03 | — | — | EP | disclosed |
| EP-0058779-A2 | Carboxamides, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1982-09-01 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4070461-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-01-24 | — | — | US | disclosed |
| US-3985730-A | 5-Alkyl-10-(aminocarbonyl/aminomethyl/cyano)-10,11-dihydro-5H-dibenz[b,f]azepine-10-alkanamines | G. D. SEARLE & CO. (US) | 1976-10-12 | — | — | US | disclosed |