Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19672721 | 0.95 | ATR (0.45) | ATRATM | |
| SCHEMBL19672660 | 0.93 | ATR (0.46) | ATRATM | |
| SCHEMBL13138348 | 0.93 | ATR (0.47) | ATRATM | |
| SCHEMBL19672659 | 0.92 | ATR (0.49) | ATRATM | |
| SCHEMBL16424880 | 0.88 | ATR (0.45) | ATRATM | |
| SCHEMBL19672814 | 0.88 | ATR (0.56) | ATRATM | |
| SCHEMBL3042006 | 0.87 | ATR (0.53) | ATRATM | |
| SCHEMBL3042008 | 0.87 | ATR (0.53) | ATRATM | |
| SCHEMBL3046231 | 0.87 | ATR (0.53) | ATRATM | |
| SCHEMBL20433552 | 0.87 | ATR (0.47) | ATRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376485-B1 | PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMA (US) | 2017-12-06 | — | — | EP | disclosed |