Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768990 | 0.82 | PTGS1 (0.58) | PTGS1 | |
| SCHEMBL12418030 | 0.82 | PTGS1 (0.58) | PTGS1 | |
| SCHEMBL14414248 | 0.75 | PTGS1 (0.38) | PTGS1 | |
| Acrylonitrile SCHEMBL9457530 | 0.72 | PTGS1 (0.47) | PTGS1 | |
| SCHEMBL15185011 | 0.71 | TDP1 (0.38) | PTGS1 | |
| SCHEMBL18927405 | 0.71 | — | — | |
| SCHEMBL17413542 | 0.71 | — | — | |
| Acetic Acid SCHEMBL27770628 | 0.71 | FFAR3 (0.50) | — | |
| SCHEMBL25452725 | 0.70 | PTGS1 (0.33) | PTGS1 | |
| SCHEMBL15492006 | 0.70 | PTGS1 (0.33) | PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252049-A1 | PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-3252050-A1 | PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-12-06 | — | — | EP | disclosed |