Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646306 | 0.91 | KDM4E (0.41) | HDAC4KDM4EATML3MBTL1KMT2A | |
| SCHEMBL20714463 | 0.84 | KDM4E (0.39) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16252752 | 0.78 | HDAC4 (0.33) | HDAC4KDM4EATML3MBTL1KMT2A | |
| SCHEMBL31149 | 0.78 | KMT2A (0.49) | KDM4EKMT2AMEN1POLBGAA | |
| SCHEMBL25886356 | 0.77 | KDM4E (0.31) | KDM4EATML3MBTL1 | |
| SCHEMBL16252462 | 0.76 | POLB (0.39) | HDAC4KDM4EATML3MBTL1KMT2A | |
| SCHEMBL16453822 | 0.75 | HDAC4 (0.36) | HDAC4KDM4EATML3MBTL1KMT2A | |
| SCHEMBL18849285 | 0.75 | EDNRA (0.34) | HDAC4KDM4EKMT2AMEN1GAA | |
| SCHEMBL20020785 | 0.74 | HDAC4 (0.39) | HDAC4KDM4EATML3MBTL1 | |
| SCHEMBL25007718 | 0.73 | HDAC4 (0.37) | HDAC4KDM4EATML3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448925-B1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORP (JP) | 2017-12-06 | — | — | EP | disclosed |