Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 3/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394922 | 0.86 | MAPT (0.55) | MAPTSMN1; SMN2AURKASYKGAA | |
| SCHEMBL29019893 | 0.86 | MAPT (0.55) | MAPTSMN1; SMN2AURKASYKGAA | |
| SCHEMBL263367 | 0.85 | JAK2 (0.47) | SMN1; SMN2SYKMAPK1EGFR | |
| SCHEMBL13166189 | 0.84 | STK17A (0.53) | MAPTAURKAEGFRKDR | |
| SCHEMBL12277575 | 0.84 | AURKA (0.51) | SMN1; SMN2AURKASYKGAARAB9A | |
| SCHEMBL266579 | 0.84 | STK17A (0.52) | MAPTSMN1; SMN2AURKAGAARAB9A | |
| SCHEMBL29535612 | 0.84 | MEN1 (0.61) | MAPTSMN1; SMN2AURKASYKGAA | |
| SCHEMBL15147773 | 0.84 | MAPT (0.53) | MAPTSMN1; SMN2AURKASYKGAA | |
| SCHEMBL22719010 | 0.84 | MEN1 (0.61) | MAPTSMN1; SMN2AURKASYKGAA | |
| SCHEMBL19313055 | 0.84 | SYK (0.72) | MAPTSMN1; SMN2AURKASYKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840080-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2017-12-06 | — | — | EP | disclosed |