Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131219 | 0.89 | AR (0.88) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL12515785 | 0.89 | AR (0.88) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL16281213 | 0.87 | AR (0.85) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL13190959 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL13190960 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL13190958 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL13191159 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL16004487 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL12988346 | 0.87 | AR (0.67) | ARHTTHIF1ALMNAHSD17B10 | |
| SCHEMBL16232997 | 0.86 | AR (0.78) | ARHTTHIF1ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252032-A1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2017-12-06 | — | — | EP | disclosed |