Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26461593 | 0.91 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267326 | 0.88 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267193 | 0.88 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL10962758 | 0.87 | HTT (0.65) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267323 | 0.87 | HTT (0.65) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19963528 | 0.83 | HTT (0.61) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267196 | 0.83 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12314718 | 0.82 | HTT (0.56) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL15258917 | 0.82 | HTT (0.56) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19677468 | 0.82 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252032-A1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2017-12-06 | — | — | EP | disclosed |