Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868711 | 0.92 | AR (0.85) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL12363856 | 0.92 | AR (0.85) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL12570312 | 0.91 | AR (0.82) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL19677336 | 0.88 | AR (0.74) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL12267331 | 0.88 | AR (0.74) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL11658489 | 0.88 | AR (0.78) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL16226561 | 0.86 | AR (0.76) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL13513140 | 0.86 | AR (0.76) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL19482753 | 0.86 | AR (0.76) | ARHTTHIF1AKMT2ATSHR | |
| SCHEMBL5250019 | 0.86 | AR (0.76) | ARHTTHIF1AKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252032-A1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2017-12-06 | — | — | EP | disclosed |