Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.55 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30489011 | 0.91 | CRBN (0.59) | CRBNKDM1AKIF11ITGB3ITGB1 | |
| Trifluoroacetic Acid SCHEMBL28310891 | 0.91 | CRBN (0.59) | CRBNKDM1AKIF11ITGB3ITGB1 | |
| Succinimide SCHEMBL434236 | 0.81 | CRBN (0.73) | CRBNITGB3ITGB1ITGAVITGA4 | |
| Succinimide SCHEMBL6036901 | 0.81 | CRBN (0.73) | CRBNITGB3ITGB1ITGAVITGA4 | |
| Succinimide SCHEMBL6717091 | 0.81 | CRBN (0.73) | CRBNITGB3ITGB1ITGAVITGA4 | |
| Trifluoroacetic Acid SCHEMBL27673776 | 0.80 | CRBN (0.55) | CRBNKDM1A | |
| Trifluoroacetic Acid SCHEMBL29657439 | 0.79 | CRBN (0.33) | CRBNITGB3ITGB1ITGAVITGA4 | |
| Trifluoroacetic Acid SCHEMBL30998099 | 0.79 | CRBN (0.65) | CRBNKDM1A | |
| Succinimide SCHEMBL9729105 | 0.78 | CRBN (0.69) | CRBNITGB3ITGB1ITGAVITGA4 | |
| Succinimide SCHEMBL30109359 | 0.78 | CRBN (0.69) | CRBNITGB3ITGB1ITGAVITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187284-A | Preparation method of cefaclor | 赵俊瑶 | 2020-05-22 | — | — | CN | claimed |
| CN-111057071-A | Preparation method of cefalexin | 刘思思 | 2020-04-24 | — | — | CN | claimed |
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| CN-107793431-B | Preparation method of cephalothin acid | 江西裕康医药有限公司 | 2021-08-24 | — | — | CN | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| CN-111187284-A | Preparation method of cefaclor | 赵俊瑶 | 2020-05-22 | — | — | CN | disclosed |
| CN-111187284-A | Preparation method of cefaclor | 赵俊瑶 | 2020-05-22 | — | — | CN | disclosed |
| CN-111057071-A | Preparation method of cefalexin | 刘思思 | 2020-04-24 | — | — | CN | disclosed |
| CN-111057071-A | Preparation method of cefalexin | 刘思思 | 2020-04-24 | — | — | CN | disclosed |
| CN-107793431-A | A kind of preparation method of the fragrant acid of cephalo thiophene | 王龙 | 2018-03-13 | — | — | CN | disclosed |
| CN-104610280-B | A kind of preparation method of cephalothin acid | 浙江东邦药业有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-104610280-A | Preparation method of cephalotin acid | ZHEJIANG EAST ASIA PHARMACEUTICAL CO LTD | 2015-05-13 | — | — | CN | disclosed |
| EP-2336105-B9 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-2336105-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8592454-B2 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-26 | — | — | US | disclosed |
| CN-102276576-B | Benzamide compound and preparation method thereof | UNIV NORTHWESTERN POLYTECHNIC | 2013-08-14 | — | — | CN | disclosed |
| CN-102276576-B | Benzamide compound and preparation method thereof | UNIV NORTHWESTERN POLYTECHNIC | 2013-08-14 | — | — | CN | disclosed |
| CN-102276576-A | benzamide compound and preparation method thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-07-21 | — | — | US | disclosed |
| EP-2336105-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | NTSR2, BDKRB1, AVPR1B | CRBN 335/4885KDM1A 3365/4885KIF11 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.