Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.61 |
| ▸ | HTR3A | P46098 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964340 | 0.84 | CHRNA7 (0.63) | CHRNA7HTR3AMEN1KMT2AATM | |
| SCHEMBL12059656 | 0.84 | CHRNA7 (0.63) | CHRNA7HTR3AMEN1KMT2AATM | |
| SCHEMBL12315101 | 0.83 | CHRNA7 (0.66) | CHRNA7HTR3AMEN1KMT2AATM | |
| SCHEMBL1963671 | 0.81 | CHRNA7 (0.70) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL2789557 | 0.81 | CHRNA7 (0.64) | CHRNA7HTR3AMEN1KMT2AATM | |
| SCHEMBL1965825 | 0.80 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL15199691 | 0.80 | CHRNA7 (0.74) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1965456 | 0.80 | CHRNA7 (0.65) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL1965159 | 0.80 | CHRNA7 (0.70) | CHRNA7HTR3ADYRK1AWNT1GSK3B | |
| SCHEMBL12059966 | 0.80 | CHRNA7 (0.70) | CHRNA7HTR3ADYRK1AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |