Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966814 | 0.96 | S1PR1 (0.63) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1968240 | 0.92 | S1PR1 (0.67) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1964698 | 0.91 | S1PR1 (0.73) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1965962 | 0.89 | S1PR1 (0.68) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1964091 | 0.87 | S1PR1 (0.66) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1489021 | 0.86 | S1PR1 (0.61) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1489125 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1970415 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1488988 | 0.85 | S1PR1 (0.59) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1488870 | 0.85 | S1PR1 (0.63) | S1PR1S1PR3ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |